Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/2853
Title: Oxidative Stress In Muscle Growth And Adaptation To Physical Exercise
Authors: Yurkevych, Igor
Keywords: oxidative stress
reactive oxygen species
muscle hypertrophy
Issue Date: 2015
Publisher: Vasyl Stefanyk Precarpathian National University
Citation: Yurkevych I. Oxidative Stress In Muscle Growth And Adaptation To Physical Exercise / I. Yurkevych // Journal of Vasyl Stefanyk Precarpathian National University. - 2015. - Vol. 2. - № 1. - P. 61-69.
Abstract: In a few last decades oxidative stress detected in a variety of physiological processes where reactive oxygen species (ROS) and reactive nitrogen species (RNS) play a central role. They are directly involved in oxidation of proteins, lipids and nucleic acids. In certain concentrations they are necessary for cell division, proliferation and apoptosis. Contractile muscle tissue at aerobic conditions form high ROS flow that may modulate a variety of cell functions, for example proliferation. However, slight increase in ROS level provide hormetic effect which may participate in adaptation to heavy weight training resulted in hypertrophy and proliferation of skeletal muscle fibers. This review will discuss ROS types, sites of generation, strategies to increase force production and achieve skeletal muscle hypertrophy.
URI: http://hdl.handle.net/123456789/2853
Appears in Collections:Vol. 2, № 1

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