Please use this identifier to cite or link to this item:
http://hdl.handle.net/123456789/2852
Title: | Amino Acids: Sensing And Implication Into Aging |
Authors: | Lushchak, Oleh Лущак, Олег Володимирович |
Keywords: | Aging Macronutrients Amino acids Sensing |
Issue Date: | 2015 |
Publisher: | Vasyl Stefanyk Precarpathian National University |
Citation: | Lushchak O. Amino Acids: Sensing And Implication Into Aging / O. Lushchak // Journal of Vasyl Stefanyk Precarpathian National University. - 2015. - Vol. 2. - № 1. - P. 51-60. |
Abstract: | An ability to sense and respond to nutrient availability is an important requisite for life. Nutrient limitation is among main factors to influence the evolution of most cellular processes. Different pathways that sense intracellular and extracellular levels of carbohydtrates, amino acids, lipids, and intermediate metabolites are integrated and coordinated at the organismal level through neuronal and humoral signals. During food abundance, nutrient-sensing pathways engage anabolism and storage, whereas limitation triggers the mechanisms, such as the mobilization of internal stores including through autophagy. These processes are affected during aging and are themselves important regulators of longevity, stress resistance, and age-related complications. |
URI: | http://hdl.handle.net/123456789/2852 |
Appears in Collections: | Vol. 2, № 1 |
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